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LTP : GluN2B on the go
Author(s) -
Matt Lucas,
Hell Johannes W
Publication year - 2014
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1002/embj.201487958
Subject(s) - long term potentiation , ampa receptor , neuroscience , nmda receptor , postsynaptic potential , neurotransmission , glutamate receptor , synaptic plasticity , biology , receptor , biochemistry
LTP , the lasting increase in synaptic transmission following heightened activity, is viewed as the physiological basis of learning. In this issue of The EMBO Journal, Dupuis et al find that certain NMDAR s diffuse away upon LTP . Antibodies against the NMDAR from patients with autoimmune synaptic encephalitis prevent this redistribution and LTP .