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Lin28a – boost your energy for youthful regeneration
Author(s) -
Burkhalter Martin D.,
Morita Yohei,
Rudolph Karl Lenhard
Publication year - 2013
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1002/embj.201387363
Subject(s) - biology , regeneration (biology) , energy (signal processing) , microbiology and biotechnology , mathematics , statistics
The regenerative capacity of most tissues declines dramatically after embryonic development and during post‐natal life. The underlying mechanisms of this phenomenon are incompletely understood. In a recent issue of Cell , Shyh‐Chang and colleagues provide experimental evidence that Lin28 prolongs youthful regenerative capacity by increasing oxidative glucose metabolism (Shyh‐Chang et al , [Shyh‐Chang N, 2013]).