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Aerial oxidation of hydrazines to nitrosamines
Author(s) -
Lunn George,
Sansone Eric D.,
Andrews A. W.,
Zeiger E.
Publication year - 1991
Publication title -
environmental and molecular mutagenesis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1
H-Index - 87
eISSN - 1098-2280
pISSN - 0893-6692
DOI - 10.1002/em.2850170109
Subject(s) - chemistry , mutagen , carcinogen , biology , organic chemistry
When 1,1‐dimethylhydrazine and N ‐aminopiperidine were deliberately exposed to air substantial amounts of the corresponding carcinogenic nitrosamines were formed. Unoxidized samples of 1,1‐dimethylhydrazine were not mutagenic while oxidized samples (which contained much higher levels of nitrosamines) were mutagenic. Both unoxidized and oxidized samples of N ‐aminopiperidine were mutagenic.