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Mutagenicity testing of ethylene oxide in Escherichia coli strains with different repair capacities
Author(s) -
Kolman Ada,
Näslund Maria
Publication year - 1987
Publication title -
environmental and molecular mutagenesis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1
H-Index - 87
eISSN - 1098-2280
pISSN - 0893-6692
DOI - 10.1002/em.2850100310
Subject(s) - escherichia coli , ethylene oxide , strain (injury) , mutagen , repressor lexa , mutation , biology , enterobacteriaceae , chemistry , microbiology and biotechnology , genetics , gene , carcinogen , organic chemistry , anatomy , repressor , transcription factor , copolymer , polymer
Mutagenicity of ethylene oxide in Escherichia coli B strains with different repair capacities was studied. Deficiencies in excision repair ( uvrA, polA ) led to a considerable increase in mutation frequency compared with that in the wild‐type strain and in strains deficient in error‐prone repair ( recA, lexA ).