Open AccessRealization of user‐friendly bioanalytical tools to quantify and monitor critical components in bio‐industrial processes through conceptual design
Author(s) -
Mandenius CarlFredrik
Publication year - 2022
Publication title -
engineering in life sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.547
H-Index - 57
eISSN - 1618-2863
pISSN - 1618-0240
DOI - 10.1002/elsc.202100116
Subject(s) - process (computing) , computer science , realization (probability) , bioprocess , management science , systems engineering , conceptual design , ranking (information retrieval) , biochemical engineering , risk analysis (engineering) , engineering , human–computer interaction , artificial intelligence , medicine , statistics , mathematics , chemical engineering , operating system
This minireview suggests a conceptual and user‐oriented approach for the design of process monitoring systems in bioprocessing. Advancement of process analytical techniques for quantification of critical analytes can take advantage of basic conceptual process design to support reasoning, reconsidering and ranking solutions. Issues on analysis in complex bio‐industrial media, sensitivity and selectivity are highlighted from users’ perspectives. Meeting challenging analytical demands for understanding the critical interplay between the emerging bioprocesses, their biomolecular complexity and the needs for user‐friendly analytical tools are discussed. By that, a thorough design approach is suggested based on a holistic design thinking in the quest for better analytical opportunities to solve established and emerging analytical needs.