Open AccessAgarose bioplastic‐based drug delivery system for surgical and wound dressings
Author(s) -
Awadhiya Ankur,
Tyeb Suhela,
Rathore Kalpana,
Verma Vivek
Publication year - 2017
Publication title -
engineering in life sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.547
H-Index - 57
eISSN - 1618-2863
pISSN - 1618-0240
DOI - 10.1002/elsc.201500116
Subject(s) - biocompatibility , agarose , drug delivery , adsorption , bioplastic , protein adsorption , materials science , biocompatible material , biomedical engineering , nanotechnology , drug , chromatography , chemical engineering , chemistry , organic chemistry , pharmacology , medicine , waste management , engineering , metallurgy
We have developed an agarose‐based biocompatible drug delivery vehicle. The vehicle is in the form of thin, transparent, strong and flexible films. The biocompatibility and haemocompatibility of the films is confirmed using direct and indirect contact biological assay. Contact angle measurement exhibits hydrophilic nature of the films, and protein adsorption test shows low protein adsorption on the film surface. Drugs, antibiotics and antiseptics, retain their potency after their incorporation into the films. Our bioplastic films can be a versatile medium for drug delivery applications, especially as wound and surgical dressings where a fast drug release rate is desired.