Agarose bioplastic‐based drug delivery system for surgical and wound dressings | Zendy

Awadhiya Ankur | Zendy; Tyeb Suhela | Zendy; Rathore Kalpana | Zendy; Verma Vivek | Zendy

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Agarose bioplastic‐based drug delivery system for surgical and wound dressings

Author(s) -

Awadhiya Ankur,

Tyeb Suhela,

Rathore Kalpana,

Verma Vivek

Publication year - 2017

Publication title -

engineering in life sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.547

H-Index - 57

eISSN - 1618-2863

pISSN - 1618-0240

DOI - 10.1002/elsc.201500116

Subject(s) - biocompatibility , agarose , drug delivery , bioplastic , adsorption , protein adsorption , biocompatible material , biomedical engineering , materials science , drug , contact angle , nanotechnology , wound dressing , wound healing , chemistry , chromatography , pharmacology , surgery , medicine , organic chemistry , composite material , waste management , engineering , metallurgy

We have developed an agarose‐based biocompatible drug delivery vehicle. The vehicle is in the form of thin, transparent, strong and flexible films. The biocompatibility and haemocompatibility of the films is confirmed using direct and indirect contact biological assay. Contact angle measurement exhibits hydrophilic nature of the films, and protein adsorption test shows low protein adsorption on the film surface. Drugs, antibiotics and antiseptics, retain their potency after their incorporation into the films. Our bioplastic films can be a versatile medium for drug delivery applications, especially as wound and surgical dressings where a fast drug release rate is desired.

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