Open AccessEngineering Microtools in Polymers to Study Cell Biology
Author(s) -
Jiang X.,
Whitesides G.M.
Publication year - 2003
Publication title -
engineering in life sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.547
H-Index - 57
eISSN - 1618-2863
pISSN - 1618-0240
DOI - 10.1002/elsc.200300051
Subject(s) - nanotechnology , soft lithography , microfluidics , lithography , materials science , optoelectronics , fabrication , medicine , alternative medicine , pathology
Recent advances in surface engineering and soft lithography provide tools to fabricate patterned surfaces and microfluidic devices with dimensions comparable to the sizes of single mammalian cells. These technologies enable the studies of individual cells on spatially well‐defined, patterned surfaces, and in contact with patterned liquid media. They provide information about cells impossible to obtain from traditional biochemical techniques.