
Enzyme based field effect transistor: State‐of‐the‐art and future perspectives
Author(s) -
Sarcina Lucia,
Macchia Eleonora,
Tricase Angelo,
Scandurra Cecilia,
Imbriano Anna,
Torricelli Fabrizio,
Cioffi Nicola,
Torsi Luisa,
Bollella Paolo
Publication year - 2023
Publication title -
electrochemical science advances
Language(s) - English
Resource type - Journals
ISSN - 2698-5977
DOI - 10.1002/elsa.202100216
Subject(s) - isfet , field effect transistor , transistor , figure of merit , materials science , nanotechnology , field (mathematics) , electrode , optoelectronics , chemistry , electrical engineering , engineering , mathematics , voltage , pure mathematics
The review discloses the historical and technological evolution of enzyme‐based field‐effect transistors (EnFETs) underlying the importance of gate electrode modification toward the implementation of novel FETs configurations such as extended‐gate FET (EG‐FETs) or EG organic FETs (EG‐OFETs). The working principle of the EnFETs as postulated by Bergveld in 1970, who defined the EnFET as an ion‐selective FET (ISFET) modified with enzyme‐membrane, is also discussed considering the analytical equations related to the EnFET output response. For each category, namely EnFETs, EG‐FETs, and EG‐OFETs, we reviewed the key devices’ configurations that addressed the research in this field in the last 40 years with particular attention to the analytical figures of merit.