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Front cover: Open‐tubular nanoelectrochromatography (OT‐NEC): gel‐free separation of single stranded DNAs (ssDNAs) in thermoplastic nanochannels
Author(s) -
Amarasekara Charuni A.,
Athapattu Uditha S.,
Rathnayaka Chathurika,
Choi Junseo,
Park Sunggook,
Soper Steven A.
Publication year - 2020
Publication title -
electrophoresis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.202070101
Subject(s) - front cover , materials science , electrochromatography , resolution (logic) , cover (algebra) , chromatography , electrophoresis , analytical chemistry (journal) , chemistry , capillary electrochromatography , capillary electrophoresis , mechanical engineering , artificial intelligence , computer science , engineering
DOI: 10.1002/elps.202000109 The front cover picture shows a single‐stranded DNA molecule moving electrokinetically through a nanochannel (100 × 100 nm, width × depth) made from the plastic poly(methylmetharcylate), PMMA, and detected using laser‐induced fluorescence. The separation, which is scale‐dependent, is based on a combination of electrophoresis and chromatography – open tubular nano‐electrochromatography (OTNEC). Baseline resolution for three model DNAs of different lengths was achieved in < 1 s using a column length of 60 μm.