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Inside Front cover: Minimization of artifact protein aggregation using tetradecyl sulfate and hexadecyl sulfate in capillary gel electrophoresis under reducing conditions
Author(s) -
Guan Qian,
Atsma Jennifer,
Tulsan Rekha,
Voronov Sergey,
Ding Julia,
Beckman Jeff,
Li Zheng Jian
Publication year - 2020
Publication title -
electrophoresis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.202070072
Subject(s) - capillary electrophoresis , sodium dodecyl sulfate , chemistry , front cover , chromatography , sulfate , electrophoresis , cover (algebra) , mechanical engineering , organic chemistry , engineering
DOI: 10.1002/elps.201900435 The inside cover picture shows the use of novel “CE‐SC X S” methods that utilize alternative detergents to SDS, such as sodium tetradecyl sulfate (STS) or sodium hexadecyl sulfate (SHS), for capillary gel electrophoresis (CGE) analysis of therapeutic mAbs. These detergents ensure maintenance of a denatured detergent:protein complex prior to and during capillary separation, as shown by the minimization of method‐induced artifacts under reducing conditions compared to the use of SDS alone. Inside cover design is by Qian Guan. The order of the covers online was updated December 23, 2020, after publication of the issue