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Front Cover: Dielectrophoresis‐assisted creation of cell aggregates under flow conditions using planar electrodes
Author(s) -
Cottet Jonathan,
Kehren Alexandre,
Lasli Soufian,
Lintel Harald,
Buret François,
FrénéaRobin Marie,
Renaud Philippe
Publication year - 2019
Publication title -
electrophoresis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201970091
Subject(s) - dielectrophoresis , electrode , trapping , microfluidics , drag , materials science , electric field , planar , voltage , optoelectronics , flow (mathematics) , nanotechnology , lab on a chip , chemistry , electrical engineering , mechanics , physics , computer science , engineering , ecology , quantum mechanics , biology , computer graphics (images)
DOI: 10.1002/elps.201800435 The cover picture shows the principle of the microfluidic chip used for the creation of cell aggregates by dielectrophoresis in flow conditions. The fluid flow, represented by the blue arrows, bring single cells in a trapping chamber where 3 electrodes are supplied with AC voltage to generate a dielectrophoretic force, represented by the red arrows which compensate the drag force and trap cells together. After 5 minutes of cell‐cell contact, the electric field is cancelled and the formed aggregate leaves the trapping chamber. Controlled aggregates can now be created and further studied directly on chip.