Premium
Back Cover: A highly sensitive aptasensor for on‐site detection of lipopolysaccharides in food
Author(s) -
Cheng Cheng,
Wu Jayne,
Chen Jiangang
Publication year - 2019
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201970053
Subject(s) - aptamer , electrokinetic phenomena , cover (algebra) , signal (programming language) , chemistry , nanotechnology , materials science , computer science , biology , microbiology and biotechnology , mechanical engineering , engineering , programming language
DOI: 10.1002/elps.201800289 The cover picture shows a rapid, highly sensitive and specific aptasensor in one‐pot single step format for lipopolysaccharides (LPS) detection. An interdigitated microelectrode (IDME) array modified with LPS‐specific aptamer is used as the sensor. During detection, a special AC measuring signal is applied over the IDME digits. The AC signal serves two purposes simultaneously, attracting the target molecules towards the IDME via AC electrokinetic effects and capacitively monitoring topological changes at the IDME surface due to aptamer‐LPS binding. The sensor can detect as low as 4.93 fg/mL LPS in 30 s.