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Front Cover: Determination of topiramate by capillary electrophoresis with capacitively‐coupled contactless conductivity detection: A powerful tool for therapeutic monitoring in epileptic patients
Author(s) -
Ishikawa Aline Akemi,
da Silva Rodrigo Moreira,
Santos Mauro Sérgio Ferreira,
da Costa Eric Tavares,
Sakamoto Americo Ceiki,
Carrilho Emanuel,
de Gaitani Cristiane Masetto,
Garcia Carlos D.
Publication year - 2018
Publication title -
electrophoresis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201870161
Subject(s) - electropherogram , analyte , capillary electrophoresis , topiramate , chromatography , capillary action , analytical chemistry (journal) , front cover , conductivity , detector , chemistry , materials science , cover (algebra) , epilepsy , optics , mechanical engineering , composite material , engineering , physics , neuroscience , biology
DOI: 10.1002/elps.201800046 The cover picture shows a capillary “absorbing” sample from a patient's vein, representing the sample extraction implemented in the work. The main target analyte (topiramate) is depicted in yellow, as one of the most common formulations of the drug (100 mg) used to treat epilepsy. The capillary also features the conductivity detector used for the presented experiments, as well as an electropherogram showing the peaks corresponding to the EOF, the main analyte, and the internal standard.