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Front Cover: Multi‐omics approach to elucidate the gut microbiota activity: Metaproteomics and metagenomics connection
Author(s) -
Guirro Maria,
Costa Andrea,
GualGrau Andreu,
MaynerisPerxachs Jordi,
Torrell Helena,
Herrero Pol,
Canela Núria,
Arola Lluís
Publication year - 2018
Publication title -
electrophoresis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201870101
Subject(s) - metaproteomics , metagenomics , gut flora , biology , computational biology , microbiome , host (biology) , bioinformatics , ecology , immunology , gene , genetics
DOI: 10.1002/elps.201700476 The cover picture shows the importance of gut microbiota in a dietary intervention and its relation with omics science. A hipercaloric diet can alter gut microbiota balance, but the supplementation with natural molecules such as hesperidin, a flavanone found in citrus fruits, can revert gut microbiota disruption. To evaluate this impact, a multiomic approach has emerged to decipher gut microbiota interaction with the host, using metagenomics and metaproteomics. Metagenomics assess the biodiversity in the gut; meanwhile metaproteomics reveal microbiota function in the host. The combination of both omics can give a real overview of the current health in the host.