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Front Cover: Multiplex identification of sepsis‐causing Gram‐negative pathogens from the plasma of infected blood
Author(s) -
Chung Boram,
Park Chulmin,
Cho SungYeon,
Shin Juyoun,
Shin Sun,
Yim SeonHee,
Lee DongGun,
Chung YeunJung
Publication year - 2018
Publication title -
electrophoresis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201870031
Subject(s) - gram negative bacteria , sepsis , gram , biology , multiplex , microbiology and biotechnology , bacteria , immunology , gene , bioinformatics , escherichia coli , genetics
DOI: 10.1002/elps.201700405 The cover picture shows the strategy for developing stuffer‐free MLPA probes targeting specific genes for five Gram‐negative pathogens and extended‐spectrum β‐lactamase (ESBL) producing Gram‐negative pathogens, and shows resulting electropherograms of each Gram‐negative pathogens. This technology can be useful for early detection of major sepsis‐causing, drug‐resistant Gram‐negative pathogens, especially the major ESBL producing pathogens in the blood of sepsis patients.