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Magnetic molecularly imprinted polymers based on silica modified by deep eutectic solvents for the rapid simultaneous magnetic‐based solid‐phase extraction of Salvia miltiorrhiza bunge , Glycine max (Linn.) Merr and green tea
Author(s) -
Li Guizhen,
Wang Xiaoqin,
Row Kyung Ho
Publication year - 2018
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201700474
Subject(s) - salvia miltiorrhiza , chemistry , daidzein , molecularly imprinted polymer , extraction (chemistry) , solid phase extraction , glycitein , chromatography , methyl gallate , epicatechin gallate , epigallocatechin gallate , gallic acid , nuclear chemistry , genistein , organic chemistry , selectivity , medicine , polyphenol , alternative medicine , pathology , traditional chinese medicine , antioxidant , catalysis
Novel magnetic molecularly imprinted polymers (MMIPs) with multiple‐template based on silica were modified by four types of deep eutectic solvents (DESs) for the rapid simultaneous magnetic solid‐phase extraction (MSPE) of tanshinone Ⅰ, tanshinone ⅡA, and cryptotanshinone from Salvia miltiorrhiza bunge ; glycitein, genistein, and daidzein from Glycine max (Linn.) Merr ; and epicatechin, epigallocatechin gallate, and epicatechin gallate from green tea , respectively. The synthesized materials were characterized by Fourier transform infrared spectroscopy and field emission scanning electron microscopy. Single factor experiments were to explore the relationship between the extraction efficiency and four factors (the sample solution pH, amount of DESs for modification, amount of adsorbent, and extraction time). It was showed that the DES4‐MMIPs have better extraction ability than the MMIPs without DESs and the other three DESs‐modified MMIPs. The best extraction recoveries with DES4‐MMIP were tanshinone Ⅰ (85.57%), tanshinone ⅡA (80.58%), cryptotanshinone (92.12%), glycitein (81.65%), genistein (87.72%), daidzein (92.24%), epicatechin (86.43%), epigallocatechin gallate (80.92%), and epicatechin gallate (93.64%), respectively. The novel multiple‐template MMIPs materials modified by DES for the rapid simultaneous MSPE of active compounds were proved to reduce the experimental steps than single‐template technique, and increase the extraction efficiency.