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Recent advances in chemiluminescence detection coupled with capillary electrophoresis and microchip capillary electrophoresis
Author(s) -
Liu Yuxuan,
Huang Xiangyi,
Ren Jicun
Publication year - 2016
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201500314
Subject(s) - capillary electrophoresis , chemiluminescence , chromatography , capillary action , chemistry , analytical chemistry (journal) , nanotechnology , materials science , composite material
CE is an ideal analytical method for extremely volume‐limited biological microenvironments. However, the small injection volume makes it a challenge to achieve highly sensitive detection. Chemiluminescence (CL) detection is characterized by providing low background with excellent sensitivity because of requiring no light source. The coupling of CL with CE and MCE has become a powerful analytical method. So far, this method has been widely applied to chemical analysis, bioassay, drug analysis, and environment analysis. In this review, we first introduce some developments for CE–CL and MCE–CL systems, and then put the emphasis on the applications in the last 10 years. Finally, we discuss the future prospects.