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Electrochemical paper‐based microfluidic devices
Author(s) -
Adkins Jaclyn,
Boehle Katherine,
Henry Charles
Publication year - 2015
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201500084
Subject(s) - microfluidics , nanotechnology , instrumentation (computer programming) , point of care testing , computer science , fabrication , mobile device , point of care , materials science , process engineering , engineering , medicine , alternative medicine , nursing , pathology , immunology , operating system
Self‐pumping porous microfluidic devices have attracted significant interest because of their low cost and broad applicability in point‐of‐care and low resource settings. One limitation of many of the devices is sensitivity and selectivity for detection. Electrochemistry can provide a sensitive, selective detection method while still using low cost, portable instrumentation as typified by handheld glucometers. Here, the development of electrochemical paper‐based analytical devices (ePADs) is reviewed. Given the importance of electrode geometry and composition, fabrication methods are reviewed first. This is followed by a review of example applications demonstrated for ePADs. Finally, major accomplishments and future directions are summarized.