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Double dispersant‐assisted ionic liquid dispersive liquid–liquid microextraction coupled with capillary electrophoresis for the determination of benzophenone‐type ultraviolet filters in sunscreen cosmetic product
Author(s) -
Ma Teng,
Li Zheng,
Niu Qian,
Li Yuanyuan,
Zhou Weihong
Publication year - 2015
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201500004
Subject(s) - benzophenone , chromatography , capillary electrophoresis , ionic liquid , ultraviolet , chemistry , dispersant , liquid liquid , materials science , organic chemistry , dispersion (optics) , optoelectronics , physics , optics , catalysis
In this work, double dispersant‐assisted ionic liquid dispersive liquid–liquid microextraction coupled with micellar electrokinetic chromatography was developed to determine four UV filters (benzophenone, 4‐hydroxybenzophenone, 2,4‐dihydroxybenzophenone, and 2‐hydroxy‐4‐methoxybenzophenone). 1‐Hexyl‐3‐methylimidazolium hexafluorophosphate was used as the extraction solvent. The main novelty of the present work was that acetonitrile‐Triton X‐114 was used as double disperser solvent. Parameters affected the extraction efficiency were investigated and optimized. Under the optimum conditions, enrichment factors were in the range of 25.3−40.5. The limits of detection and quantitation, calculated at a S/N of three and ten, were 3.9−6.7 ng/mL and 13.0−22.3 ng/mL. The linearity of the method was in the range of 0.02−2 μg/mL for 2, 4‐dihydroxybenzophenone and 4‐hydroxybenzophenone, 0.01−2 μg/mL for benzophenone and 2‐hydroxy‐4‐methoxybenzophenone, with correlation coefficient ( R 2 ) of 0.9984−0.9991. The proposed method was successfully applied to the determination of four benzophenone‐type UV filters in six kinds of sunscreen cosmetic products, with yielded relative recoveries ranging from 80.2 to 117.7%.