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The potential of the capillary electrophoresis techniques for quality control of biopharmaceuticals—A review
Author(s) -
Tamizi Elnaz,
Jouyban Abolghasem
Publication year - 2015
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201400343
Subject(s) - capillary electrophoresis , flexibility (engineering) , biopharmaceutical , biochemical engineering , quality (philosophy) , computer science , nanotechnology , chromatography , chemistry , materials science , engineering , microbiology and biotechnology , mathematics , biology , physics , statistics , quantum mechanics
CE is considered as a powerful technique in biopharmaceutical industry, owing to its inherent advantages such as high resolution, efficient separation, and its flexibility to couple with high‐sensitive detecting methods. Present review provides a summary of the applications of CE‐based methods in the quality control of biopharmaceuticals according to the papers published between 1994 and July 2014. This article is divided into the sections based on different CE modes applied in the analysis of biopharmaceuticals and gives detailed information about the employed experimental conditions. At the end some overall conclusions and perspectives are given.