Premium
Capillary electrophoretic methods for the screening and determination of pharmacologic adulterants in herbal‐based pharmaceutical formulations
Author(s) -
Moreira Ana Paula L.,
Martini Mariele,
Carvalho Leandro M.
Publication year - 2014
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201400059
Subject(s) - capillary electrophoresis , chromatography , chemistry
This review aims to describe the CE methods utilized for the determination of adulterants in herbal‐based formulations marketed for different therapeutic purposes. The CE methods for screening and determination of pharmacologic adulterants are reviewed on the basis of the CE techniques and their detection methods. CZE and MEKC methods coupled to optical (UV), capacitively coupled contactless conductivity, and MS detection modes are discussed and reviewed. Worldwide adulteration cases related to pharmaceutical formulations containing herbs as the main active products are presented covering all the works published in the last four decades.