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Recent advances in capillary electrophoretic migration techniques for pharmaceutical analysis
Author(s) -
Deeb Sami El,
Wätzig Hermann,
ElHady Deia Abd,
Albishri Hassan M.,
Griend Cari Sängervan,
Scriba Gerhard K. E.
Publication year - 2014
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201300411
Subject(s) - capillary electrophoresis , electrophoresis , capillary action , chemistry , chromatography , materials science , composite material
Since the introduction about 30 years ago, CE techniques have gained a significant impact in pharmaceutical analysis. The present review covers recent advances and applications of CE for the analysis of pharmaceuticals. Both small molecules and biomolecules such as proteins are considered. The applications range from the determination of drug‐related substances to the analysis of counterions and the determination of physicochemical parameters. Furthermore, general considerations of CE methods in pharmaceutical analysis are described.