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Nanostructured CaCO 3 ‐poly(ethyleneimine) microparticles for phenol sensing in fluidic microsystem
Author(s) -
MayorgaMartinez Carmen C.,
Hlavata Lenka,
Miserere Sandrine,
LópezMarzo Adaris,
Labuda Jan,
Pons Josefina,
Merkoçi Arben
Publication year - 2013
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201300056
Subject(s) - microsystem , fluidics , detection limit , ethyleneimine , materials science , glutaraldehyde , microfluidics , biosensor , nanotechnology , repeatability , chromatography , chemistry , polymer , aerospace engineering , engineering , composite material
A new and simple strategy based on nanostructured CaCO 3 ‐poly(ethyleneimine) (PEI) microparticles (MPs) for phenol sensing using PDMS/glass fluidic microchip is developed. This fluidic microsystem including integrated screen‐printed electrodes modified with CaCO 3 ‐PEI MPs and tyrosinase (Tyr) through cross‐linking with glutaraldehyde, represents a low‐cost platform for phenol detection. The designed fluidic microsystem improves the sensitivity of the biosensor allowing the detection of very low concentrations of phenol (up to 10 nM). This device shows high repeatability and low detection limit, is easy to be fabricated, inexpensive, disposable, and amenable to mass production.