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Graphene oxide coated capillary for chiral separation by CE
Author(s) -
Ye Nengsheng,
Li Jian,
Xie Yali,
Liu Chang
Publication year - 2013
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201200516
Subject(s) - graphene , raman spectroscopy , capillary action , oxide , ephedrine , analytical chemistry (journal) , structural isomer , reproducibility , pseudoephedrine , chromatography , coating , materials science , spectroscopy , chemistry , nanotechnology , organic chemistry , composite material , optics , physics , neuroscience , biology , quantum mechanics
This article describes a new application of graphene oxide ( GO ) in CE based on the coating of fused silica capillary for chiral separation. The coated capillary was characterized by SEM , energy dispersive X‐ray spectroscopy, and Raman spectra. The results indicated that the capillary was coated with GO . Chiral separations were carried out in the GO ‐coated capillary for the ephedrine–pseudoephedrine ( E ‐ PE ) isomers and β‐methylphenethylamine (β‐Me‐PEA) isomers at the optimal buffer conditions without any chiral selector by CE . The precision and reproducibility of GO ‐coated capillary were investigated, and the RSD s of migration time ( n = 6) for the E ‐ PE isomers were 1.35–1.41%, and 0.97–3.50% for β‐Me‐ PEA isomers, respectively. The LOD for E ‐ PE isomers and β‐Me‐ PEA isomers was 3 μM and 18 μM, respectively.