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Porous membrane structures as stationary phase for capillary electrochromatography
Author(s) -
Kopeć Karina K.,
Wessling Matthias,
Stamatialis Dimitrios F.
Publication year - 2012
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201200275
Subject(s) - capillary electrochromatography , electro osmosis , membrane , phase inversion , porosity , polymer , chemical engineering , polysulfone , electrochromatography , zeta potential , chromatography , fabrication , spinning , chemistry , materials science , polymer chemistry , electrophoresis , capillary electrophoresis , nanotechnology , organic chemistry , biochemistry , nanoparticle , engineering , medicine , alternative medicine , pathology
This work presents the application of membrane technology for the fabrication of stationary phase for CEC columns using the technique based on phase inversion of polymer solution. A blend of polyimide P 84 and sulphonated poly(ether ether ketone was processed via immersion precipitation dry‐wet spinning into small‐bore porous fiber. The morphology, zeta potential, and performance of the porous structure in the CEC separation were investigated. Noncharged molecules (as markers of the electroosmotic flow) and small organic compounds were injected into the column, driven under the application of voltage, and detected on the electropherogram. The proof of concept of applying porous membrane structure as stationary phase for CEC was shown and possible optimization to improve efficiency and selectivity was suggested.