Premium
Enhanced separation of C ompound X ueshuantong capsule using functionalized carbon nanotubes with cationic surfactant solutions in MEEKC
Author(s) -
Cao Jun,
Li Ping,
Chen Jue,
Tan Ting,
Dai HanBin
Publication year - 2013
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201200101
Subject(s) - cationic polymerization , pulmonary surfactant , microemulsion , chemistry , dispersion (optics) , carbon nanotube , chemical engineering , aqueous solution , chromatography , context (archaeology) , extraction (chemistry) , organic chemistry , paleontology , biochemistry , physics , optics , biology , engineering
A novel additive of multi‐walled carbon nanotubes ( MWNT s) dispersed with cationic surfactants or mixed cationic/anionic surfactants was used for MEEKC separation of eight phenolic compounds, four glycosides, and one phenanthraquinone. In this context, several parameters affecting MEEKC separation were studied, including the dispersion agents of MWNT s, MWNT s content, oil type, SDS concentration, and the type and concentration of cosurfactant. Compared with conventional MEEKC , the addition of all types of MWNT s dispersions using single or mixed cationic surfactant solutions in running buffers was especially useful for improving the separation of solutes tested, as they influenced the partitioning between the oil droplets and aqueous phase due to the exceptional electrical properties and large surface areas of MWNT s. Use of cationic surfactant‐coated MWNT s (6.4 μg/mL) as the additive in a microemulsion buffer (0.5% octanol, 2.8% SDS , 5.8% isopropanol, and 5 mM borate buffer) yielded complete resolution of 13 analytes. The proposed method has been successfully applied for the detection and quantification of the studied compounds in a complex matrix sample ( C ompound X ueshuantong capsule).