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Current development of microfluidic immunosensing approaches for mycotoxin detection via capillary electromigration and lateral flow technology
Author(s) -
Li Peiwu,
Zhang Zhaowei,
Zhang Qi,
Zhang Ning,
Zhang Wen,
Ding Xiaoxia,
Li Ran
Publication year - 2012
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201200050
Subject(s) - mycotoxin , microfluidics , electromigration , microfluidic chip , nanotechnology , capillary electrophoresis , capillary action , current (fluid) , biochemical engineering , materials science , chromatography , chemistry , microbiology and biotechnology , biology , engineering , composite material , electrical engineering
Mycotoxin contamination in the food chain has caused serious health issues in humans and animals. Thus, a rapid on‐site and lab‐independent detection method for mycotoxins, such as aflatoxins (AFTs), is desirable. Microfluidic chip based immunosensor technology is one of the most promising methods for fast mycotoxin assays. In this review, we cover the major microfluidic immunosensors used for mycotoxin analysis, via flow‐through (capillary electromigration) and lateral flow technology. Sample preparation from different matrices of agricultural products and foodstuffs is summarized. The choice of materials, fabrication strategies, and detection methods for microfluidic immunosensors are further discussed in detail. The sensors application in mycotoxin determination is also outlined. Finally, future challenges and opportunities are discussed.