Premium
Capillary electrophoresis determination of nonsteroidal anti‐inflammatory drugs in wastewater using hollow fiber liquid‐phase microextraction
Author(s) -
Villar Navarro Mercedes,
Ramos Payán María,
FernándezTorres Rut,
BelloLópez Miguel A.,
Callejón Mochón Manuel,
Guiráum Pérez Alfonso
Publication year - 2011
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.201100105
Subject(s) - chromatography , naproxen , aceclofenac , ketoprofen , capillary electrophoresis , chemistry , extraction (chemistry) , diclofenac , ibuprofen , ketorolac , wastewater , polyvinyl alcohol , analgesic , pharmacology , organic chemistry , medicine , biochemistry , alternative medicine , pathology , engineering , waste management
The presence of pharmaceuticals in the environment due to growing worldwide consumption has become an important problem that requires analytical solutions. This paper describes a CE determination for several nonsteroidal anti‐inflammatory drugs (ibuprofen, naproxen, ketoprofen, diclofenac, ketorolac, aceclofenac and salicylic acid) in environmental waters using hollow fiber membrane liquid‐phase microextraction. The extraction was carried out using a polypropylene membrane supporting dihexyl ether and the electrophoretic separation was performed in acetate buffer (30 mM, pH 4) using ACN as the organic modifier. Detection limits between 0.25 and 0.86 ng/mL were obtained, respectively. The method could be applied to the direct determination of the seven anti‐inflammatories in wastewaters, and five of them have been determined or detected in different urban wastewaters.