Premium
Cellulose dimethylphenylcarbamate‐immobilized zirconia for chiral separation in reversed‐phase CEC
Author(s) -
Gwon Jurim,
Jin Juhyeon,
McNeff Clayton V.,
Park Jung Hag
Publication year - 2009
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200900057
Subject(s) - enantiomer , cellulose , chemistry , resolution (logic) , phase (matter) , chromatography , cubic zirconia , analyte , chiral stationary phase , phosphate , organic chemistry , ceramic , artificial intelligence , computer science
Cellulose dimethylphenylcarbamate (CDMPC)‐immobilized zirconia (CDMPCZ) was used as a chiral stationary phase for enantioseparation of a set of nine racemic compounds in reversed‐phase CEC. Influences of the type and composition of organic modifier and the applied voltage on enantioseparation were examined. Separation data on CDMPCZ were also compared with those on CDMPC‐immobilized silica (CDMPCS). Enantiomers of the analytes investigated are well separated in ACN/phosphate buffer mobile phases. Better enantioselectivity and resolution were obtained with ACN than MeOH as the organic modifier. Retention was longer but better enantioselectivity and resolution were obtained on CDMPCZ than CDMPCS.