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CE‐TOF/MS: Fundamental concepts, instrumental considerations and applications
Author(s) -
Staub Aline,
Schappler Julie,
Rudaz Serge,
Veuthey JeanLuc
Publication year - 2009
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200800782
Subject(s) - reflectron , acceleration , computer science , biomolecule , biochemical engineering , nanotechnology , materials science , chemistry , physics , engineering , ion , time of flight mass spectrometry , organic chemistry , classical mechanics , ionization
This review discusses the fundamental principles of TOF analyzers and covers the great progress that has been made in this area in recent years ( i.e. orthogonal acceleration, reflectron). This paper also gives an overview of applications performed by CE coupled to TOF/MS detection. The main domains of interest include the analysis of biomolecules and natural compounds.