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Continuous particle separation by size via AC‐dielectrophoresis using a lab‐on‐a‐chip device with 3‐D electrodes
Author(s) -
Çetin Barbaros,
Kang Yuejun,
Wu Zhemin,
Li Dongqing
Publication year - 2009
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200800464
Subject(s) - dielectrophoresis , microchannel , electrode , materials science , particle (ecology) , inlet , lab on a chip , microfluidics , mechanics , tracking (education) , chip , volumetric flow rate , flow (mathematics) , particle size , nanotechnology , mechanical engineering , physics , electrical engineering , engineering , chemical engineering , psychology , pedagogy , oceanography , quantum mechanics , geology
Abstract In this paper, we present a novel, simple lab‐on‐a‐chip device for continuous separation of particles by size. The device is composed of a straight rectangular microchannel connecting two inlet reservoirs and two exit reservoirs. Two asymmetric, 3‐D electrodes are embedded along the channel wall to generate a non‐uniform electrical field for dielectrophoresis. Particles with different sizes are collected at the different exit reservoirs. Main flow is induced by pressure difference between the inlet and the exit reservoirs. The device is used successfully for the separation of the 5 and 10 μm latex particles and for the separation of yeast cells and white blood cells. A numerical simulation based on Lagrangian tracking method is used to simulate the particle motion and the results showed a good agreement with the experimental data.