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Manipulation of self‐assembly amyloid peptide nanotubes by dielectrophoresis
Author(s) -
Castillo Jaime,
Tanzi Simone,
Dimaki Maria,
Svendsen Winnie
Publication year - 2008
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200800260
Subject(s) - dielectrophoresis , nanotechnology , materials science , biosensor , photolithography , silicon dioxide , electrode , peptide , microfluidics , chemistry , composite material , biochemistry
Self‐assembled amyloid peptide nanotubes (SAPNT) were manipulated and immobilized using dielectrophoresis. Micro‐patterned electrodes of Au were fabricated by photolithography and lifted off on a silicon dioxide layer. SAPNT were manipulated by adjusting the amplitude and frequency of the applied voltage. The immobilized SAPNT were evaluated by SEM and atomic force microscopy. The conductivity of the immobilized SAPNT was studied by I – V characterization, for both single SAPNT and bundles. This work illustrates a way to manipulate and integrate biological nanostructures into novel bio‐nanoassemblies with concrete applications, such as field‐effect transistors, microprobes, microarrays, and biosensing devices.