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Capillary electrophoresis‐electrospray‐mass spectrometry in peptide analysis and peptidomics
Author(s) -
Herrero Miguel,
Ibañez Elena,
Cifuentes Alejandro
Publication year - 2008
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200700404
Subject(s) - capillary electrophoresis , chromatography , mass spectrometry , peptide , capillary electrophoresis–mass spectrometry , electrospray , chemistry , analytical chemistry (journal) , electrospray ionization , biochemistry
Abstract In the present work, an exhaustive review of the main developments and applications of CE‐MS for peptide analysis is given. This review includes the use of different CE separation modes, MS analyzers, capillary coatings, preconcentration techniques, on‐chip applications as well as other different multidimensional strategies for peptide analysis. Key applications are critically discussed and relevant works published from January 2000 to May 2007 are summarized including information concerning the type of sample, CE‐MS parameters as well as some figures of merit of the different CE‐MS procedures developed for peptide analysis and peptidomics.