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Evaluation of carbon nanostructures as chiral selectors for direct enantiomeric separation of ephedrines by EKC
Author(s) -
MolinerMartínez Yolanda,
Cárdenas Soledad,
Valcárcel Miguel
Publication year - 2007
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200600773
Subject(s) - carbon nanotube , enantiomer , ephedrine , pulmonary surfactant , chirality (physics) , enantiomeric excess , materials science , chemistry , nanotechnology , chemical engineering , chromatography , organic chemistry , enantioselective synthesis , catalysis , biochemistry , neuroscience , engineering , biology , chiral symmetry breaking , physics , quantum mechanics , quark , nambu–jona lasinio model
Single‐walled nanotubes and multi‐walled nanotubes (MWNTs) have been evaluated as chiral selectors for the enantiomeric separation of ephedrines by using EKC with surfactant‐coated carbon nanotubes. The analysed compounds were (±)‐ephedrine, (±)‐norephedrine and (±)‐ N ‐methylephedrine. The potential of those carbon nanostructures as chiral selectors has been evaluated by changing different experimental variables such as pH, addition of organic modifiers, potential and injection time. The capability of MWNTs to resolve enantiomeric mixtures was demonstrated by using partial filling of the capillary with concentrated surfactant‐coated MWNTs. Differences in the enantioselectivity were discussed.