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Recent advances in the control of morphology and surface chemistry of porous polymer‐based monolithic stationary phases and their application in CEC
Author(s) -
Eeltink Sebastiaan,
Svec Frantisek
Publication year - 2007
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200600573
Subject(s) - porosity , polymer , morphology (biology) , chemical engineering , chemistry , surface (topology) , nanotechnology , materials science , geology , organic chemistry , paleontology , engineering , geometry , mathematics
Abstract This review focuses on developments in the field of polymer‐based monolithic columns for CEC published in the literature since the beginning of the year 2005. The possibility of in‐situ preparation as well as easy control over their porous properties and surface chemistries clearly make monolithic separation media an attractive alternative to capillary columns packed with particles. Different variables such as polymerization conditions, morphology, and surface chemistry are shown to directly affect performance of monolithic capillary columns in terms of efficiency, analysis time, and retention.