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Accelerated multiple‐pass moving average: A novel algorithm for baseline estimation in CE and its application to baseline correction on real‐time bases
Author(s) -
Solis Alejandro,
Rex Mathew,
Campiglia Andres D.,
Sojo Pedro
Publication year - 2007
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200600538
Subject(s) - baseline (sea) , algorithm , moving average , computer science , filter (signal processing) , computer vision , oceanography , geology
We present a novel algorithm for baseline estimation in CE. The new algorithm which we have named as accelerated multiple‐pass moving average (AMPMA) is combined to three preexisting low‐pass filters, spike‐removal, moving average, and multi‐pass moving average filter, to achieve real‐time baseline correction with commercial instrumentation. The successful performance of AMPMA is demonstrated with simulated and experimental data. Straightforward comparison of experimental data clearly shows the improvement AMPMA provides to the linear fitting, LOD, and accuracy (absolute error) of CE analysis.