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Experimental and numerical investigation into leakage effect in injectors of microfluidic devices
Author(s) -
Tsai ChienHsiung,
Wang YaoNan,
Lin ChiuFeng,
Yang RueyJen,
Fu LungMing
Publication year - 2006
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200500913
Subject(s) - injector , electrokinetic phenomena , leakage (economics) , microfluidics , materials science , mechanics , computer science , nanotechnology , mechanical engineering , engineering , physics , economics , macroeconomics
This paper performs an experimental and numerical investigation into low‐leakage injectors designed for electrophoresis microchips. The principal material transport mechanisms of electrokinetic migration, fluid flow, and diffusion are considered in developing a mathematical model of the electrophoresis process. Low‐leakage injectors designed with injection channels orientated at various included angles are designed and tested. The numerical and experimental results indicate that the injector with a 30° included angle successfully minimizes sample leakage and has an exciting potential for use in high‐quality, high‐throughput chemical analysis procedures and in many other applications in the field of micro‐total analysis systems.