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Analysis of melamine resins by capillary zone electrophoresis with electrospray ionization‐mass spectrometric detection
Author(s) -
Cook Helmy A.,
Klampfl Christian W.,
Buchberger Wolfgang
Publication year - 2005
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200410058
Subject(s) - melamine , chromatography , capillary electrophoresis , chemistry , mass spectrometry , electrospray ionization , capillary electrophoresis–mass spectrometry , electrospray , analytical chemistry (journal) , resolution (logic) , organic chemistry , artificial intelligence , computer science
A method for the determination of the major components of (methoxymethyl)melamine resins, with quantitative analysis of unreacted melamine by capillary zone electrophoresis (CZE) using electrospray ionization‐mass spectrometry (ESI‐MS) is presented. Using a low background electrolyte (BGE) pH, components are separated according to their charge/ionic radius ratio with a distinctly different separation selectivity compared to the HPLC methods commonly employed in melamine‐resin analysis. The use of a time‐of‐flight mass spectrometer (TOF‐MS) was concluded to be necessary, as the complex samples studied required maximum sensitivity and resolution, which is clearly superior for TOF‐MS detectors over their quadrupole counterparts. A standard curve of free melamine was determined with an R 2 = 0.999 over a concentration range of an order of magnitude. This method offers the unique separation selectivity of CZE as well as a quicker analysis time, especially for dimers compared to the HPLC methods used to date.