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Capillary electrophoresis and mass spectrometry for screening of metabolic disorders in newborns
Author(s) -
Šenk Petr,
Kozák Libor,
Foret František
Publication year - 2004
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200405853
Subject(s) - capillary electrophoresis , mass spectrometry , chromatography , capillary electrophoresis–mass spectrometry , chemistry , electrospray ionization
Clinical analyses always represent a challenge for the sensitivity and selectivity of the analytical techniques. Of the most critical are the techniques required for the quick determination of the disease state and application of the proper treatment in newborns. This short critical review overviews the present state of the art of the use of mass spectrometry and capillary electrophoresis for screening of metabolic disorders in newborns.