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Advances in capillary electrochromatography and micro‐high performance liquid chromatography monolithic columns for separation science
Author(s) -
LegidoQuigley Cristina,
Marlin Nicola D.,
Melin Virginie,
Manz Andreas,
Smith Norman W.
Publication year - 2003
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200390136
Subject(s) - capillary electrochromatography , electrochromatography , monolithic hplc column , methacrylate , chromatography , capillary action , high performance liquid chromatography , polymerization , monolith , acrylate , polymer , materials science , styrene , monomer , chemistry , capillary electrophoresis , copolymer , organic chemistry , composite material , catalysis
Over the last decade, monoliths or continuous beds have emerged as an alternative to traditional packed‐bed columns for use in capillary electrochromatography (CEC) and micro‐high performance liquid chromatography (μ‐HPLC). Monolithic columns can be divided into two categories: silica‐based monolithic columns and rigid organic polymer‐based monolithic columns resulting from the polymerization of acrylamide, styrene, acrylate or methacrylate monomers. In this paper, the chemistry and most recent applications of these various types of monoliths in both CEC and μ‐HPLC are presented.