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On‐chip potential gradient detection with a portable capillary electrophoresis system
Author(s) -
Feng HuaTao,
Wei HongPing,
Y. Li Sam F.
Publication year - 2004
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200305734
Subject(s) - miniaturization , capillary electrophoresis , chromatography , chip , capillary action , electrophoresis , chemistry , analytical chemistry (journal) , materials science , nanotechnology , computer science , telecommunications , composite material
A portable chip‐CE system with potential gradient detection (PGD) was developed and applied to the determinations of alkali metals and alkaloids. The separation efficiency appeared to be satisfactory and nonaqueous capillary electrophoresis (NACE) proved to be applicable to PGD or conductivity detection. The power supplies, separation and detection were built on a device of 3 kg in weight. A branch channel near the end of the separation channel was designed to perform PGD and make the application of relatively high field strength possible. The study is the first report on the application of PGD on the microchip platform. The design of the chip‐CE system shows several advantages, such as simplicity, miniaturization and wide applicability.