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Capacitively coupled contactless conductivity detection in capillary electrophoresis
Author(s) -
Zemann Andreas J.
Publication year - 2003
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200305476
Subject(s) - capillary electrophoresis , capillary electrochromatography , capillary action , analyte , materials science , galvanic cell , conductivity , chromatography , analytical chemistry (journal) , chemistry , composite material , metallurgy
Capacitively coupled contactless conductivity detection (C 4 D) has become an accepted detection method in capillary electrophoresis (CE) for a variety of analytes. Advantages of this technique over optical detection modes and galvanic contact conductivity detection include great flexibility in capillary handling and rather simple mechanical parts and electronics, as it can be performed in an on‐capillary mode. Furthermore, the detection principle can be used with capillaries made of other materials than fused silica (PEEK®, Teflon®), with chip‐based separation technologies, or with capillaries having very small inner diameters. This review presents a discussion of the published literature on C 4 D for CE and capillary electrochromatography.