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Theory of DNA electrophoresis (∼ 1999 –2002 ½)
Author(s) -
Slater Gary W.,
Guillouzic Steve,
Gauthier Michel G.,
Mercier JeanFrançois,
Kenward Martin,
McCormick Laurette C.,
Tessier Frédéric
Publication year - 2002
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.200290002
Subject(s) - field (mathematics) , nanotechnology , data science , capillary electrophoresis , proteomics , computational biology , computer science , biology , materials science , genetics , microbiology and biotechnology , mathematics , gene , pure mathematics
Over the last two decades, the introduction of new methods such as pulsed‐field gel electrophoresis and capillary array electrophoresis has made it possible to map and sequence entire genomes, including our own. The development of these experimental methods has been helped by the progress of theoretical and computational sciences, and the interactions between these three modi operandi of modern science are still pushing the limits of our technologies. We now see a clear trend towards proteomics and microfluidic (even nanofluidic!) devices. In this review, we take a look at the progress of the field over the last 3 years using the glasses of the theoretical scientist and focusing mostly on new ideas and concepts. About a dozen different subfields are discussed and reviewed. We conclude by giving a commented list of some of the best review articles published over the last 2–3 years.