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Separation of chiral compounds by capillary electrophoresis
Author(s) -
Verleysen Katleen,
Sandra Pat
Publication year - 1998
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.1150191607
Subject(s) - capillary electrophoresis , chromatography , chemistry , electrophoresis , capillary action , capillary electrochromatography , separation (statistics) , materials science , computer science , machine learning , composite material
This review presents the different chiral selectors used in capillary electrophoresis (CE) for the separation of enantiomers. The use of charged cyclodextrins, crown ethers, polysaccharides, proteins, natural and synthetic micelles, macrocyclic antibiotics and ergot alkaloids is discussed in detail. Neutral native and derivatized cyclodextrins are not treated because several review articles have already been published on this topic. Recent developments like the application of two chiral selectors in the same background electrolyte are highlighted.