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Chiral capillary electrophoresis with noncyclic oligo‐and polysaccharide chiral selectors
Author(s) -
Sutton Richard M. C.,
Sutton Karen L.,
Stalcup Apryll M.
Publication year - 1997
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.1150181220
Subject(s) - capillary electrophoresis , polysaccharide , chromatography , chemistry , electrophoresis , combinatorial chemistry , organic chemistry
A number of noncyclic oligo‐ and polysaccharides have been used as chiral additives in capillary electrophoresis (CE). This review offers a broad survey of the types of oligo‐ and polysaccharides which have been investigated and also some of the conditions developed for the enantioseparation of a wide range of drugs and other racemic compounds. Details of enantioseparation mechanisms are also discussed, in addition to some of the parameters required for optimization of the enantioresolution of chiral molecules.