Affinity capillary electrophoresis | Zendy

Rippel Geza | Zendy; Corstjens Hugo | Zendy; Billiet Hugo A. H. | Zendy; Frank Johannes | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Affinity capillary electrophoresis

Author(s) -

Rippel Geza,

Corstjens Hugo,

Billiet Hugo A. H.,

Frank Johannes

Publication year - 1997

Publication title -

electrophoresis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.666

H-Index - 158

eISSN - 1522-2683

pISSN - 0173-0835

DOI - 10.1002/elps.1150181208

Subject(s) - capillary electrophoresis , affinity electrophoresis , chemistry , ligand (biochemistry) , electrophoresis , feature (linguistics) , chromatography , combinatorial chemistry , affinity chromatography , biochemistry , enzyme , receptor , philosophy , linguistics

The application of affinity capillary electrophoresis (ACE) to the study of molecular interactions is reviewed. ACE appears to be a sensitive, versatile and convenient tool to obtain reliable data on binding constants and stoichiometries of interacting systems using the Hummel‐Dreyer method and variants thereof. A powerful feature is the possibility to analyze simultaneously the affinity of a large number of compounds for the same ligand, making it a promising tool for the screening of large combinatorial libraries.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research