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Gel electrophoretic mobility of charged particles in a medium with curved channels
Author(s) -
Fridrikh Serguei,
Gotlib Yulii,
Belenkij Boris
Publication year - 1997
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.1150180107
Subject(s) - electrophoresis , chemical physics , chemistry , channel (broadcasting) , polymer , materials science , nanotechnology , chromatography , composite material , computer science , computer network
A model of electrophoretic mobility of small charged particles (for example short DNA fragments) in media with curved channels is proposed. The medium is represented by a dense material embedding the curved channels accessible to the charged particles. The steady flow method is used to obtain an analytical expression of the particles' electrophoretic mobility as a function of the channel's shape. The analogy between the statistical properties of the channels and polymer chains (free‐jointed and with the persistent mobility mechanism) is used.