Channel thickness variations could degrade resolution in electrophoresis | Zendy

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Channel thickness variations could degrade resolution in electrophoresis

Author(s) -

Holzwarth George

Publication year - 1996

Publication title -

electrophoresis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.666

H-Index - 158

eISSN - 1522-2683

pISSN - 0173-0835

DOI - 10.1002/elps.1150171016

Subject(s) - streamlines, streaklines, and pathlines , discontinuity (linguistics) , laplace's equation , slab , distortion (music) , channel (broadcasting) , resolution (logic) , laplace transform , mechanics , geometry , materials science , physics , optics , mathematical analysis , mathematics , computer science , differential equation , optoelectronics , amplifier , geophysics , computer network , quantum mechanics , cmos , artificial intelligence

Variations in the lateral dimensions of capillaries and ultrathin gels along their length could lead to a distortion of the sample zone because charged particles traveling near the wall must travel a longer distance under a smaller field than particles traveling along the centerline. The size of the effect is computed by solving Laplace's equation for the potential everywhere in a conducting slab with a discontinuity in thelateral dimensions and integrating the travel time along different streamlines.

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