An informativity index for multilocus DNA fingerprints | Zendy

Krawczak Michael | Zendy; Lubjuhn Thomas | Zendy

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An informativity index for multilocus DNA fingerprints

Author(s) -

Krawczak Michael,

Lubjuhn Thomas

Publication year - 1995

Publication title -

electrophoresis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.666

H-Index - 158

eISSN - 1522-2683

pISSN - 0173-0835

DOI - 10.1002/elps.1150160105

Subject(s) - index (typography) , dna profiling , fingerprint (computing) , dna , computational biology , biology , chemistry , genetics , computer science , artificial intelligence , world wide web

An informativity index for multilocus DNA fingerprints, r , was developed. It is based upon the Shannon information that a paternal DNA fingerprint conveys about the offspring phenotype pattern. Both simulation and empirical data reveal that the index r is strongly correlated with the mean log likelihood ratio (paternity vs . nonpaternity) expected in trio cases of true paternity. Since r can be estimated from DNA fingerprints of unrelated individuals in advance, it will provide an easy means to assess the potential utility of a given probe/enzyme combination in kinship testing.

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