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Enantiomer separation using mobile and immobile cyclodextrin derivatives with electromigration
Author(s) -
Mayer Sabine,
Schurig Volker
Publication year - 1994
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.11501501118
Subject(s) - electromigration , enantiomer , cyclodextrin , chemistry , separation (statistics) , chromatography , materials science , stereochemistry , computer science , composite material , machine learning
The principle of electrochromatography is applied to enantiomer separation with wall‐coated capillaries of 50μm (ID). As chiral stationary phase an immobilized polysiloxane containing chemically bonded monokis‐6‐ O ‐octamethylene‐permethyl‐cyclodextrin (β‐ or γ‐Chirasil‐Dex) was used. The results are compared with the conventional method of adding cyclodextrin derivatives as chiral pseudostationary phase to the running buffer.